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Desktop sonication device –
Diagenode One

The Diagenode One is the new desktop solution that provides small volume DNA and chromatin shearing for optimal sample prep.* Designed to fit any bench, it is the smallest and lightest Diagenode shearing device. The fully integrated cooling system and the all-new 20 and 50 µl microfluidic chips have been enhanced to deliver the highest performance.

Ideal for:

  • DNA shearing for Next-Generation-Sequencing
  • Chromatin shearing for ChIP analysis with small samples

Key application notes and publications

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Technical specifications

Shearing DNA shearing 200 bp – 1 kb
Throughput 1 sample
Volumes 20 and 50 µl
Unit dimensions 20 [W] x 28.5 [D] x 16.5 [H] cm
7.9 [W] x 11.2 [D] x 6.5 [H] in
Weight 5 kg (11 lb)


Catalogue number Description
DIAG-C30150001 Diagenode One 20 µL Microfluidic chips – 10rxn
DIAG-C30150002 Diagenode One 50 µL Microfluidic chips – 10rxn

Other shearing instruments

Bioruptor Pico

Bioruptor Pico
Latest innovation in shearing

NGS sample preparation

Bioruptor Plus

Bioruptor Plus
Advanced water bath sonicator

Cell and tissue sample preparation
Sample preparation for mass spectrometry analysis

Megaruptor 2

Megaruptor® 2
Hydrodynamic shearing instrument

Superior solution for long read sequencing library preparation

Please refer to this chart to compare shearing instruments for NGS.

* LGC’s distribution agreement includes EMEA, South America and Canada for all market sectors and the United States for the agricultural biotechnology sector.