Nutritional and fitness biomarkers
LGC has developed a series of breakthrough biomarker assays to assist health and nutrition programmes in both industry and academia:
Assays available for applications relating to various disease states, including:
Assays to monitor biomarkers relating to efficacy within an administration study. Particularly suited for development of novel nutraceutical products. Examples include:
Monitoring of vitamin levels
Monitoring of carotenoid levels
Monitoring of phytoestrogen levels (such as isoflavones and lignans, etc)
Monitoring pharmacokinetic profiles of novel nutraceutical ingredients. For example:
Phytoestrogen levels (isoflavones such as genistein or daidzein, or metabolites such as equol, etc).
Wide range of assays available that can be used in longitudinal studies relating to long term impact on health and nutrition. For example:
Phytoestrogen monitoring: applied to breast and prostate cancer investigations in the EPIC study, etc.
Notoriously inaccurate, food diaries used during trials may be underpinned by assays which provide accurate and dependable data using a range of markers including:
Sucrose/ fructose monitoring
Vitamin and carotenoid level monitoring.
Assays developed to monitor compliance in clinical trials. A dietary component is administered alongside a therapeutic preparation and nutritional biomarkers monitored as a means of ‘tracking’ patient compliance during the study, including monitoring of phytoestrogen level.In addition, compliance of dietary regimens during a clinical trial can also be evaluated, as well as potential drug-diet interactions.
Monitoring carotenoid and vitamin levels
Monitoring phytoestrogen level.
In December 2010 LGC acquired HFL Sport Science. All services offered by HFL now form part of the LGC Group. To read more on this story, please visit LGC news.