Cookies on the
LGC website
We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we’ll assume that you are happy to receive all cookies on the LGC website. However, if you would like to, you can change your cookie settings at anytime.
Question markFind out more

Flow Cytometry

Flow Cytometry Service

With the growth of the biopharmaceuticals industry, the impact of biological drugs on the immune system has been a key area of investigation for pre-clinical and clinical drug development. Flow cytometry provides an ideal tool to examine this impact, allowing the interrogation of immunological changes at the level of a single cell to define drug related effects.

LGC’s Flow Cytometry service offers a range of assays to support pre-clinical to late phase drug development. With two 13-colour, Beckman Coulter CytoFLEX cytometers LGC is well equipped to meet your bioanalytical needs. Both instruments are fully validated to meet the both the GLP and GCP regulatory guidelines.

Complex Assay Development

LGC has a breadth of experience in the development of complex cytometry end-points, in both human samples and a range of pre-clinical species. These include:

• Immunophenotyping
• Receptor Occupancy
• Intracellular cytokines
• Phospho-flow
• Cellular activation
• nAbs

Regulating Flow

No formal guidance is available on the validation of assays from regulated bodies, which can make the validation of these highly complex assay challenging. LGC has extensive experience in fit-for-purpose flow cytometry method validation and offers a full method development and validation service which meets current industry standards.

If you would like further information about our Flow Cytometry services, please contact us.