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Nutritional and fitness biomarkers

LGC has developed a series of breakthrough biomarker assays to assist health and nutrition programmes in both industry and academia:

Health monitoring: Assays available for applications relating to various disease states, including:
  • Cancer
  • Diabetes
  • Heart disease
  • Obesity
  • Osteoporosis
Efficacy evaluation: Assays to monitor biomarkers relating to efficacy within an administration study. Particularly suited for development of novel nutraceutical products. Examples include:
  • Monitoring of vitamin levels
  • Monitoring of carotenoid levels
  • Monitoring of phytoestrogen levels (such as isoflavones and lignans, etc)
     
Pharmacokinetic studies: Monitoring pharmacokinetic profiles of novel nutraceutical ingredients. For example:
  • Phytoestrogen levels (isoflavones such as genistein or daidzein, or metabolites such as equol, etc).
Epidemiological studies: Wide range of assays available that can be used in longitudinal studies relating to long term impact on health and nutrition. For example:
  • Phytoestrogen monitoring: applied to breast and prostate cancer investigations in the EPIC study, etc.
Food diaries: Notoriously inaccurate, food diaries used during trials may be underpinned by assays which provide accurate and dependable data using a range of markers including:
  • Sucrose/ fructose monitoring
  • Vitamin and carotenoid level monitoring.
Compliance monitoring: Assays developed to monitor compliance in clinical trials. A dietary component is administered alongside a therapeutic preparation and nutritional biomarkers monitored as a means of ‘tracking’ patient compliance during the study, including monitoring of phytoestrogen level.In addition, compliance of dietary regimens during a clinical trial can also be evaluated, as well as potential drug-diet interactions.

These include:
  • Monitoring carotenoid and vitamin levels
  • Monitoring phytoestrogen level.

In December 2010 LGC acquired HFL Sport Science. All services offered by HFL now form part of the LGC Group. To read more on this story, please visit LGC news.
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