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Quantitation of low level impurities using LC-MS/MS in GMP analysis

  • Date:
  • 25 Feb 2016
  • Duration:
  • 30-45 Minutes, 2:30-3:15pm GMT

LC-MS/MS has been the technique of choice for trace organic analysis in most areas of analytical chemistry for over a decade and is now slowly but steadily becoming so in GMP pharmaceutical analysis. LC-MS/MS offers unrivalled sensitivity and selectivity as well as speed of analysis. 

LGC webinar on Quantitation of low level impurities using LC-MS/MS in GMP analysis

LGC has a long history of analytical excellence and expertise in quantitative LC-MS/MS analysis. Within CMC Analytical Services, our LC-MS/MS experts develop and validate quick, sensitive and reliable methods and the technique is routinely applied to the GMP analysis of genotoxins, leachables, degradants and cleaning agents as well as proteins and peptides for purposes of drug development, stability testing and batch release.

During this webinar, Dr Ellen Vringer-Stokvis, Sector Manager within CMC Analytical Services at LGC, will cover the following:

  • Briefly touch on the theory of LC-MS/MS, and subsequently discuss the strengths and challenges of the technique.
  • Case studies of impurity methods will be presented including a mini-focus on the notoriously difficult quantitation of peptides and proteins from natural extracts.
  • Provide an opportunity for Q&A

This webinar is aimed at GMP project managers and Chromatographers with limited or no MS experience.

Date: Thursday 25 February 2016
Time: 2:30 - 3:15 PM GMT

Register for the webinar on Quantitation of low level impurities using LC-MS/MS in GMP analysis