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Advanced water bath sonication -
Bioruptor Plus

The Bioruptor® Plus uniformly processes multiple samples in sealed tubes of 0.5 ml to 50 ml capacity.* The instrument includes a built-in cooling system with a water cooler and single cycle valve to ensure high precision temperature control, resulting in higher quality samples. Bioruptor Plus is an all-in-one solution for shearing chromatin, cell and tissue disruption and many other applications.

Ideal for:

  • Chromatin shearing 200 bp – 1 kb
  • ChIP-qPCR
  • Mass spectrometry
  • Chemical applications

Key application notes and publications


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Technical specifications

Shearing Chromatin shearing 200 bp - 1 kb
Throughput 12 samples (0.5 ml tube holder)
6 samples (1.5 and 15 ml tube holder)
3 samples (50 ml tube holder)
Volumes 100 µl (0.5 ml tubes)
100 - 300 µl (1.5 ml tubes)
300 µl - 2 ml (15 ml tubes)
2 - 20 ml (50 ml tubes)
Control unit dimensions 35 [W] x 26 [D] x 16.5 [H] cm
13.8 [W] x 10.2 [D] x 6.5 [H] in
Soundproof box dimensions 35 [W] x 35 [D] x 26.5 [H] cm
13.8 [W] x 13.8 [D] x 10.4 [H] in
Weight 30 kg (66.1 lb)

Accessories, consumables and QC kits

Catalogue number Description
DIAG-B01200015 Bioruptor Plus and Pico 15 ml sonication accessories
DIAG-B01200011 Bioruptor Plus tube holder 1.5 ml
DIAG-B01200013 Bioruptor Plus tube holder 15 ml
DIAG-B01200014 Bioruptor Plus tube holder 50 ml
DIAG-C30010013 Bioruptor Plus 0.5 ml TPX tubes – 500 pc
DIAG-C30010010 Bioruptor Plus 1.5 ml TPX tubes – 300 pc
DIAG-C30010009 Bioruptor Plus 15 ml TPX tubes – 50 pc
DIAG-C40010001 Bioruptor Plus DNA QC Kit – 1 pc

Other shearing instruments

Bioruptor Pico

Bioruptor Pico
Latest innovation in shearing

ChIP-seq
NGS sample preparation

Megaruptor 2

Megaruptor® 2
Hydrodynamic shearing instrument

Superior solution for long read sequencing library preparation

Diagenode One

Diagenode One
Desktop sonication device

Compact bench top device for simple NGS library preparation

Please refer to this chart to compare shearing instruments for NGS.

* LGC’s distribution agreement includes EMEA, South America and Canada for all market sectors and the United States for the agricultural biotechnology sector.