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Impact of our work

The work carried out by LGC in our role as the UK National Measurement Laboratory and Designated Institute for chemical and bio-measurement has a significant impact on the world through improving confidence in measurement and supporting innovation within measurement science.

Our work addresses the measurement challenges facing the UK and the wider world, influencing policy, protecting consumers and enhancing quality of life.

Case studies showing recent examples of the impact our work has on health, environment, food and security can be found below.
 
Non-invasive tumour diagnostics: validating reference standards (health)
LGC scientists developed digital PCR methods for the evaluation and application of Horizon Discovery Group's new Cell Free DNA Reference Standards which contain cancer-related DNA mutations.
LGC extends its calibration facility to include qNMR (health, environment, food, security)
LGC scientists are using advanced technologies to ensure high purity reference standards are produced more quickly and cost-effectively to support the growing global industries that are reliant on measurements.
LGC supporting healthcare: ensuring reproducible molecular results from research to the clinic (health)
A high accuracy approach to molecular
quantification for the diagnosis of tuberculosis
(TB) has highlighted the potential measurement
limitations when using bacterial DNA as
a biomarker for clinical trial efficacy.
Halting horsemeat contamination: providing standards (food)
LGC played a crucial role in helping the UK government address the 2013 horsemeat issue by rapidly developing reference standards for meat species and providing the first proficiency testing scheme.
Reducing your chance of rejection (health)
LGC scientists contribute to reducing the likelihood of organ rejection by developing reference methods and materials to support therapeutic drug monitoring and sharing their measurement expertise with front-line hospital laboratories to help them provide better patient care.
Securing UK borders (security)
LGC scientists have provided UK national
security stakeholders with an improved
understanding of the technologies used to
detect drugs and explosives.
Developing an international consensus for reference material production (health, environment, food, security)
LGC experts contributed to the conversion of ISO Guide 34 to ISO 17034 to support evolving regulatory need.
LGC supporting innovation: working with Malvern Instruments (environment, health)
Through LGC’s measurement science function, we
have contributed to expanding the capabilities of a
novel nanoparticle tracking technology.
Blood, sweat and tears (health)
LGC has developed a transportable 'pin prick' blood test to help elite athletes achieve success.
Priority water pollutants – meeting the measurement challenge

Priority water pollutants – meeting the measurement challenge (environment)
LGC scientists have developed a method for the quantification of low levels of priority pollutants in complex environmental matrices, to support the implementation of the EU Water Framework Directive.

Setting the standards (environment, food)
LGC has produced the world's first reference material certified for carbon isotope ratios traceable to the SI (International System of Units).
 
Microbial profiling – unlocking the potential with metagenomic control materials Microbial profiling – unlocking the potential with metagenomic control materials (health)
LGC scientists have shown how the development and application of control materials can assist in the interpretation of molecular microbial community profiling experiments, helping to increase the accuracy of DNA sequencing methods.
Peanut allergen quantification: a tough nut to crack (food, health)
Development of a food matrix peanut allergen quality control material that contains a known amount of allergen protein.

New digital PCR reporting guidelines for molecular diagnostics (health, food)
LGC scientists have collaborated on the development of best practice guidelines for the reporting of digital Polymerase Chain Reaction (PCR) data.

A new tool for proteomic analysis (health, food)
LGC scientists have produced a prototype quality assurance material to improve the robustness of protein analysis.

Food with thought: evaluating food supplements for consumer safety (food)
Development of a range of reference materials to ensure food and supplement manufacturers can verify the composition and safety of their products.
 
Alzheimer’s disease diagnosis: the end of the guessing game? Alzheimer’s disease diagnosis: the end of the guessing game? (health)
LGC scientists are collaborating on the development of a non-invasive diagnostic technique for early detection of Alzheimer’s disease.

Our case study archive contains links to older case studies.

 

Current developments

Read our latest publications to find out more about our science.



Contact us

For further information contact the National Measurement System helpdesk.

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