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DNA extraction kits

oktopure DNA extraction robot

Download our extractions brochure

Sample material can vary greatly in consistency as well as in sugar, protein and fat composition - all of which can affect the quality and purity of the extracted nucleic acid and the subsequent performance of downstream applications. To provide the most efficient and effective extraction method LGC offers not only a range of different extraction technologies but also the capacity to develop tailor-made kit systems optimised to a particular application.

The table below describes a number of the key features of each of our extraction kit technologies.

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  sbeadex™ mag™ Kleargene silica Kleargene spin
Matrix

Surface-modified superparamagnetic particles

Modified magnetic particles

Silica particles

Glass fibre solid support

Mechanism of action(1) Novel two-step binding mechanism Classic polarity-based binding mechanism Classic polarity-based binding mechanism;  Classic polarity-based binding mechanism; 
Format 96-well 96-well  single tubes 96 and 384-well
Flexibility scalable protocols scalable protocols low to high volume extractions spin columns
Optimised matrices Plant material, forensic samples, tissue and cells, bacterial cultures Whole blood, buffy coat, buccal swabs, bacteria, yeast, fungi Blood, tissue and saliva samples

Plant tissue typically 100ng to 10µg

Grade of automation Automated high-throughput extraction Automated high-throughput extraction Manual extraction Semi-automated high throughput extraction
Benefits
  • No organic solvents or chaotropic salts in final wash buffers
  • No drying of beads for evaporation of alcohols
  • High flexibility of all extraction parameters
  • High flexibility of all extraction parameters
  • High yields
  • Extractions up to 10 mL blood samples
  • Ideal for manual format extraction products
  • Flexible lysis solutions available
  • Suitable for manual or (semi) automated extraction solutions
  • 96 or 384 format

(1) Our surface-coated superparamagnetic particles do not require the use of vacuum filtration or centrifugation steps, hence they are well-suited to automation.